Medical images from Hospitals consist of a 2D data set, providing information of human body as sectioned slices. The human body has morphological structure in 3D space. Therefore, to recognize human organs, 3D reconstruction process is necessary to be reformed using 2D slice. After this, its precise position and shape can be identified. Medical 3D volume image is based on unprocessed 3D medical data which contain a variety of medical information. This session cover details on IEEE 3333.2.1 which discusses medical 3D technology and 3D volume image’s safety and quality and describes the generation and practical use of medical 3D modeling for diagnostics and therapeutic applications.