Organizers: Kirill Larin, David Douglas Sampson
This tutorial will overview recent advances in the development and application of optical imaging techniques for the biomechanical assessment of soft tissues and cells – so-called optical elastography. Emerging optical methods are providing opportunities to make such assessments on the meso-scale between tissues and cells. The advantages of such methods for imaging and sensing of various tissues and disease progression in tissues and cells will be explained. Special emphasis will be devoted to the theory and applications of a novel technique – optical coherence elastography (OCE) – the use of optical coherence tomography to perform elastography. This tutorial will start with the basic description of light-tissue interactions, including structural and optical models of tissues based on single and multiple scattering. It will then describe the basics of optical coherence tomography and other imaging techniques used in optical elstography. The basic theory and taxonomy of optical elastography will be described, with an emphasis on the strongly emerging techniques of optical coherence elastography and Brillouin microscopy. Examples of applications in medicine and cell biology will be provided, including tumor imaging and sensing, ophthalmic treatment and disease monitoring, embryology, and dermatology, amongst others.
Intended Audience: Engineers, scientists, students, postdocs, and physicians will find this course useful if interested in learning about optical imaging/microscopy and how they are applied to study the biomechanical properties of tissues and cells, optical instrument design, and biophotonics applications in medical science and clinical diagnosis and treatment.
Presenters (title of talks TBA)
Kirill V. Larin is a Professor of Biomedical Engineering at the University of Houston, USA. His research contributions include development and application of optical methods for noninvasive imaging and diagnostics of tissues and cells. He has authored more than 120 peer-reviewed publications in the area of imaging and biophotonics. He is Fellow of OSA and SPIE.
David D. Sampson is a Professor of Electrical Engineering at Univ. Western Australia, Australia, and Vice-Provost Research & Innovation at Univ. Surrey, UK. His interests are in translational biophotonics and fiber-optic imaging devices, and in optical elastography methods and applications. He is a fellow of IEEE, OSA and SPIE and Director, SPIE (2017-2019).